AVAC ND-LASOTA

DISCRIPTION AND ACTION:
    Avac ND-LaSota is a vaccine for protection from Newcastle Disease (ND). The La Sota strain of Newcastle Disease Virus is classified as stronger Lentogenic strain as compare to Hitchner B1 strain. This is a live virus vaccine for the vaccination of chicks 7 day or older booster vaccination and stimulation of active humoral immunity against virulent ND in chicken.
 

COMPOSITION:
    Each dose of vaccine contains at least 106EID50 attenuated Newcastle Disease virus strain La Sota and lyophilization stabilizers.
 

INDICATION:
    This product is recommended for re-vaccination of chick for prevention of Newcastle Disease in the 2nd-4th week of age and also use for booster vaccination during the laying period. It will induce local immunity in chicken, from day of vaccination onwards.
    First vaccination may be given to birds at 7-10 days of age by oral drop or via drinking water. Vaccine can be administered in drinking water to older birds. It takes 10 to 14 day for humoral immunity to appear. Immunity may last for 4 - 8 weeks. It is desirable that vaccine is used as a booster vaccine in birds primed with Lentogenic vaccines.
 

PREPARATION OF VACCINE AND METHOD OF VACCINATION:
    Take out the vaccine vial from cold storage just before vaccination and place in ice bath. Remove cap of the diluent bottle and fix the provided hypodermic needle (20G) on the spout. Remove the plastic flip-off seal from the vaccine vial and transfer 1-2ml diluent into it by inserting the needle and squeezing the bottle.Very gently shake the vaccine vial (avoid vigorous shaking to prevent frothing) and use the diluent bottle as a pump to withdraw reconstituted vaccine into the diluent bottle.
    For oral drop administration: Hold the chicks firmly in one hand and open the mouth of the chick by pressing mandibular joint. Place one drop (one dose) on in the mouth and close the beak with fingers.
    For drinking water administration: Reconstitute the vaccine as described earlier. Pour the reconstituted vaccine into another clean vessel containing approximately 4 liters. Mix well and distribute according to the table below which also gives the quantity of skim milk powder (SMP) to be added for stabilization of vaccine during administration.

Method of vaccination

    Discontinue all medication and disinfectant from drinking water 24 hours before and up to 24 hours after vaccination. Rinse and flush waterers with clean non-sanitized water. Water starve the flock for at least 2 hours prior to vaccination. Provide adequate space so that at least two thirds of birds can drink at a time.  
 

WARNING
- Vaccinate the primed chickens with Newcaslte Disease Lentogenic vaccines.
- Use only the sterile diluent supplied with the vaccine.
- Do not expose vaccine to either direct sunlight and extreme heat during vaccination.
- Use all the vaccine content at the first open.
- Burn all containers and unused vaccine according to the regulation.
 

STORAGE
- Store at 2^oC- 8^oC, protected from direct sunlight.
 

PACK SIZE
- Vial: 50; 100; 200; 500 and 1000 doses
- Container: 10 vials per box or 50 vials per box
 

SHELF-LIFE: Best before 24 months from manufacture